Personal Information

Fields of Interest and Expertise

- subcellular and extracellular trafficking of proteins.

- role of extracellular vesicles in diagnosis and disease.

- clinical biochemistry of monoclonal gammopathies.

Teaching

- Specialized Clinical Biochemistry (part of the course of Laboratory Medicine, MSc in Medical Biotechnology)

- Clinical Biochemistry applied to sport activities (part of the course of Biology and Biochemistry, BSc in Motor sciences)

- Clinical Biochemistry (part of the course of Biogenetics and Clinical Sciences, BSc in Technical of Biomedical Laboratory).

- Clinical Biochemistry (School of Specialization of Biochemistry and Clinical Chemistry)

Curriculum vitae

2000: MSc, Industrial Biotechnology at University of Bologna (110/110 cum laude). 

2002-2003: Visiting phD student at The Scripps Research Institute, La Jolla, CA(USA). Advisor: Prof. F.Romersberg

2004: PhD, Applied biocatalysis and Industrial biotechnology, at University of Bologna. Advisor: Prof. A.Hochkoeppler.

2004-2005: Postdoctoral Associate, University of Brescia, Department of Biomedical sciences and Biotechnology.

2005-present: Assistant Professor of Clinical Biochemistry and Molecular Biology, University of Brescia, Department of Molecular and Traslational Medicine.

• Brescia

• Polyclonal versus monoclonal immunoglobulin-free light chains quantification. Annals of Clinical Biochemistry (2015)
• Comparison of Hevylite™ IgA and IgG assay with conventional techniques for the diagnosis and follow-up of plasma cell dyscrasia. Annals of Clinical Biochemistry (2015)
• Immunoglobulin free light chains and GAGs mediate multiple myeloma extracellular vesicles uptake and secondary NfκB nuclear translocation. Frontiers in Immunology (2014)
• C-src Enriched Serum Microvesicles Are Generated in Malignant Plasma Cell Dyscrasia. PLoS ONE (2013)
• The epsilon hinge-ear region regulates membrane localization of the AP-4 complex. Traffic (2011)
• Decreased type I interferon receptor-soluble isoform in antiretroviral-treated HIV-positive children. Journal of Interferon and Cytokine Research (2008)
• Technical note: Simultaneous identification of CSN1S2 A, B, C, and E alleles in goats by polymerase chain reaction-single strand conformation polymorphism. Journal of Dairy Science (2008)
• Tyrosine83 is essential for the activity of E. coli galactoside transacetylase. Biochimica et Biophysica Acta - Proteins and Proteomics (2007)
• Expanding the Substrate Repertoire of a DNA Polymerase by Directed Evolution. Journal of the American Chemical Society (2004)
• Silencing of the gene coding for the ε subunit of DNA polymerase III slows down the growth rate of Escherichia coli populations. FEBS Letters (2003)
• Directed evolution of β-galactosidase from Escherichia coli by mutator strains defective in the 3′→5′ exonuclease activity of DNA polymerase III. FEBS Letters (2001)
• Expression of the RNA recognition motif-containing protein SEB-4 during Xenopus embryonic development. Mechanisms of Development (2000)