Personal Information

Fields of Interest and Expertise

Conformational Analysis of Biomolecules in Solution.

Host-guest inclusion compounds.

Ligand-Macromolecules Interaction as observed by Nuclear Relaxation Analysis.

“In vivo” NMR studies of cell metabolism.

Calix[n]arenes.

Liposome as drug-carrier.

Curriculum Vitae

Dec 1993: Degree in Chemistry and Pharmaceutical Technology, at the University of Siena (110 cum laude/110). Thesis title: "Conformation and Dynamics of Rifaximin and Rifaximin OR by NMR studies".

1993-1994: E.E.C grant on Environmental Assessment.

1994-1998: PhD in Chemistry at the University of Siena. Title: " Combined theoretic and experimental methods to define the conformation of biomolecules in solution ". Advisor: Prof. C. Rossi (University of Siena).

1997: Honorary Research Assistant in the Department of Biochemistry and Molecular Biology of the University College of London in the NMR group of Dr. Paul Driscoll.

1999-2002: Grant in Chemistry at the University of Siena. Title: " Conformational and dynamical analysis of macromolecules in solution and their complex with metallic ions". Advisor: Prof. C. Rossi (University of Siena).

2002-2005: Grant at the University of Siena. Title: " In Vivo 13C-NMR and Modelling Study of Metabolic Yield Response to Ethanol Stress in a Wild-Type Strain of Saccharomyces cerevisiae ".

2006-present: Research fellow at the Dept. of Pharmaceutical and Applied Chemistry of the University of Siena.

• Siena - STCDB

• Effect of quercetin, rutin, naringenin and epicatechin on lipid peroxidation induced in human sperm. Reproductive Toxicology (2012)
• Using liposomes as carriers for polyphenolic compounds: The case of Trans-resveratrol. PLoS ONE (2012)
• Metabolic response to exogenous ethanol in yeast: An in vivo statistical total correlation NMR spectroscopy approach. Journal of Biosciences (2012)
• Increased Susceptibility to Resveratrol of Helicobacter pylori Strains Isolated from Patients with Gastric Carcinoma. JOURNAL OF NATURAL PRODUCTS (2011)
• A PVA/PVP hydrogel for human lens substitution: Synthesis, rheological characterization, and in vitro biocompatibility. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2011)