Personal Information

Fields of Interest and Expertise

Cellular damages induced by oxidative stress and defense mechanisms elicited by antioxidants

Detection of biomarkers of oxidative stress

Glutathione dependant detoxification of xenobiotics

Nitric oxide, S-nitrosothiols and other NOx: detection and function

Potential therapeutic compounds releasing H2S, evaluation of their biological effect and of their influence on the levels of endogenous antioxidants

Teaching

Pharmacology

Curriculum Vitae

1992: Degree in Biological Sciences, University of Siena

1992-1995: Fellowship at the Tecnobiochip (Marciana, LI), at the University “La Sapienza” in Rome and at the Pharmacia Research Center (Milan)

1995-1998: Ph student at the Institute of Pathologic Anatomy, University of Siena.

1999: PhD in Diagnostic Pathology, University of Siena

1998-2001: Research Technician at the University of Siena2001-: Researcher, Assistant Professor, Pharmacology and Toxicology, University of Siena

2010: Visiting Researcher at the Department of Medicine, University of Texas Health Science Center at San Antonio, Texas (USA).

• Siena - STCDB

• A step-by-step protocol for assaying protein carbonylation in biological samples. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2015)
• Insulin administration: Present strategies and future directions for a noninvasive (possibly more physiological) delivery. Drug Design, Development and Therapy (2015)
• Dietary Intake of Proteins and Calories Is Inversely Associated With The Oxidation State of Plasma Thiols in End-Stage Renal Disease Patients. Journal of Renal Nutrition (2015)
• Micro-method for the determination of glutathione in human blood. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2014)
• Pathophysiology of tobacco smoke exposure: Recent insights from comparative and redox proteomics. Mass Spectrometry Reviews (2014)