logotype

PHYSICO-CHEMICAL CHARACTERIZATION OF ANHYDROUS D-MANNITOL

Research Area: Uncategorized Year: 2009
Type of Publication: Article
Authors:
Journal: JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY Volume: 95
Number: 3 Pages: 871-876
Month: March
ISSN: 1388-6150
Note:
15th International Conference on Biological Calorimetry, Univ Pecs, Pecs, HUNGARY, MAY 24-30, 2008
Abstract:
In this work the solid-state characterization of anhydrous D-mannitol has been performed: alpha and beta modifications can be distinguished only by XRPD and FTIR as they show melting temperature and enthalpy that are the same within the standard deviation. The understanding of the thermal behaviour of the delta form (obtained by re-crystallization in acetone) has required XRPD experiments performed at variable temperature. This form during heating undergoes a solid phase transition to alpha modification. By cooling a melted sample, under a wide range of experimental conditions, a very fast crystallization occurs. Independently of the starting crystal form (beta or delta form), the re-crystallization of D-mannitol from melt always leads to alpha form.
[ Back ]
Copyright © CSGI 2012 - Credits - Cookie Policy - Privacy - Consorzio per lo Sviluppo dei Sistemi a Grande Interfase, via della Lastruccia 3, 50019, Sesto Fiorentino, Italy