Consorzio Interuniversitario per lo sviluppo dei Sistemi a Grande Interfase
Center for Colloid and Surface Science

Personal information

Position: Post-Doc

Email: alessio.nocentini@unifi.it

Phone: +39 055 4573685

Location: Firenze


Fields of Interest and Expertise

Medicinal Chemistry Drug Design Organic Chemistry, Molecular Modelling, Enzymology

Teaching

Docente di Analisi dei Medicinali I – modulo II B030128 (B054) CdLM in Farmacia, Scuola di Scienze della salute umana

Curriculum Vitae

2014–2017 PhD cum laude in Area del Farmaco e Trattamenti Innovativi: Curriculum Scienze Farmaceutiche (Medicinal Chemistry), NEUROFARBA Department, University of Florence - PhD Supervisor: Prof. Paola Gratteri 2008–2014 MSc, 110/110 cum laude in Pharmaceutical Chemistry and Technology, Pharmacy, University of Florence CURRENT AND PREVIOUS POSITION 2023–present RTD-b (Assistant Professor, SSD CHIM/08), NEUROFARBA Department, University of Florence, Italy 2020–2023 RTD-a (Assistant Professor, SSD CHIM/08), NEUROFARBA Department, University of Florence, Italy 2017–2020 Postdoctoral research fellowships, Supervisor: Prof. Claudiu T. Supuran, Prof. Paola Gratteri, NEUROFARBA Department, University of Florence

Awards

Premio Miglior Tesi di Dottorato 2018, Divisione di Chimica Farmaceutica, Società Chimica Italiana

Unit

Publications

Development of Penicillin-Based Carbonic Anhydrase Inhibitors Targeting Multidrug-Resistant Neisseria gonorrhoeae

- Bonardi A. - Nocentini Alessio - Giovannuzzi S. - Paoletti N. - Ammara A. - Bua S. - Abutaleb N.S. - Abdelsattar A.S. - Clemente Capasso - Gratteri P. - Flaherty D.P. - Seleem M.N. - Supuran C.T.
Journal of Medicinal Chemistry

Leveraging SARS-CoV-2 Main Protease (Mpro) for COVID-19 Mitigation with Selenium-Based Inhibitors

- De Luca V. - Angeli A. - Nocentini Alessio - Gratteri P. - Pratesi S. - Tanini D. - Carginale V. - Capperucci A. - Supuran C.T. - Clemente Capasso
International journal of molecular sciences

CD73 Inhibitors as Antitumor Agents

- Clemente Capasso - Nocentini Alessio - Supuran C.T.
Topics in Medicinal Chemistry

Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII

- Balašova A. - Pustenko A. - Nocentini Alessio - Daniela Vullo - Supuran C.T. - Žalubovskis R.
Journal of Enzyme Inhibition and Medicinal Chemistry

Biochemical, structural, and computational studies of a γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei

- Di Fiore A. - De Luca V. - Langella E. - Nocentini Alessio - Buonanno M. - Monti S.M. - Supuran C.T. - Clemente Capasso - De Simone G.
Computational and Structural Biotechnology Journal

Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum

- Giovannuzzi S. - De Luca V. - Nocentini Alessio - Clemente Capasso - Supuran C.T.
Journal of Enzyme Inhibition and Medicinal Chemistry

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