Consorzio Interuniversitario per lo sviluppo dei Sistemi a Grande Interfase
Center for Colloid and Surface Science

Personal information

Position: Permanent Staff

Email: a.hochkoeppler@unibo.it

Phone: 051 2093-671

Location: Bologna


Fields of Interest and Expertise

Gene silencing in prokaryotes.

Enzymes structure and kinetics.

Overexpression and purification of proteins.

Protein engineering.

Synthetic Biology.

Industrial enzymes.

 

Curriculum Vitae


1982: Degree in Crop Sciences, at the University of Bologna (110 cum laude/110). Title: "Effect of Sowing Season on Productivity of Vicia faba".

1983-1987: PhD in Crop Sciences, at the University of Bologna. Title: "Investigations on soybean: a) inoculation of soil with Rhizobium  japonicum; b) solubilization of soybean mitochondria in reverse  micelles". Advisor: Prof. G. Venturi (University of Bologna); co-advisor: Prof. P.L. Luisi (Federal Institute of Technology, Zurich, Switzerland).

1987-1998: Studies and research activity at: Institute for Industrial Crops (Bologna, Italy); Institute for Plant Physiology (CNR, Milano, Italy); Federal Institute of Technology (Zurich, Switzerland); Department of Biology, University of Bologna (Bologna, Italy); Max Planck Institute for Biophysical Chemistry (Göttingen, Germany); Institut für Biologie II, University of Freiburg (Freiburg, Germany); Department of Chemistry and Biochemistry, University of Arizona (USA).

1998: fellow of the “Advanced Bacterial Genetics” course, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

1998-present: Associate Professor at the Department of Industrial Chemistry of the University of Bologna.

Unit

Publications

Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme

- Iacovino L.G. - Rossi M. - Di Stefano G. - Rossi V. - Binda C. - Brigotti M. - Tomaselli F. - Pasti A.P. - Dal Piaz F. - Cerini S. - Alejandro Hochkoeppler
Biochimie

Production in Escherichia coli of recombinant COVID-19 spike protein fragments fused to CRM197

- Bellone M.L. - Puglisi A. - Dal Piaz F. - Alejandro Hochkoeppler
Biochemical and Biophysical Research Communications

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