Consorzio Interuniversitario per lo sviluppo dei Sistemi a Grande Interfase
Center for Colloid and Surface Science

Personal information

Position: Permanent Staff

Email: claudia.bonechi@unisi.it

Phone: 0577 234-372

Location: Siena


Fields of Interest and Expertise

Conformational Analysis of Biomolecules in Solution.

Host-guest inclusion compounds.

Ligand-Macromolecules Interaction as observed by Nuclear Relaxation Analysis.

“In vivo” NMR studies of cell metabolism.

Calix[n]arenes.

Liposome as drug-carrier.

 

Curriculum Vitae

Dec 1993: Degree in Chemistry and Pharmaceutical Technology, at the University of Siena (110 cum laude/110). Thesis title: "Conformation and Dynamics of Rifaximin and Rifaximin OR by NMR studies".

1993-1994: E.E.C grant on Environmental Assessment.

1994-1998: PhD in Chemistry at the University of Siena. Title: " Combined theoretic and experimental methods to define the conformation of biomolecules in solution ". Advisor: Prof. C. Rossi (University of Siena).

1997: Honorary Research Assistant in the Department of Biochemistry and Molecular Biology of the University College of London in the NMR group of Dr. Paul Driscoll.

1999-2002: Grant in Chemistry at the University of Siena. Title: " Conformational and dynamical analysis of macromolecules in solution and their complex with metallic ions". Advisor: Prof. C. Rossi (University of Siena).

2002-2005: Grant at the University of Siena. Title: " In Vivo 13C-NMR and Modelling Study of Metabolic Yield Response to Ethanol Stress in a Wild-Type Strain of Saccharomyces cerevisiae ".

2006-present: Research fellow at the Dept. of Pharmaceutical and Applied Chemistry of the University of Siena.

Unit

Publications

Design, Synthesis and Characterization of a Visible-Light-Sensitive Molecular Switch and Its PEGylation Towards a Self-Assembling Molecule

- Paolino M. - Saletti M. - Reale A. - Licciardi M. - VarvarĂ  P. - Marquette A. - LĂ©onard J. - Claudia Bonechi - Alessandro Donati - Giorgi G. - Giuliani G. - Carlotti B. - Ortica F. - Loredana Latterini - Gentile M. - Paccagnini E. - Olivucci M. - Cappelli A.
Chemistry - A European Journal

Click-Chemistry Cross-Linking of Hyaluronan Graft Copolymers

- Saletti M. - Paolino M. - Ballerini L. - Giuliani G. - Gemma Leone - Lamponi S. - Andreassi M. - Claudia Bonechi - Alessandro Donati - Piovani D. - Schieroni A.G. - Agnese Magnani - Cappelli A.
Pharmaceutics

Spontaneous polymerization of benzofulvene derivatives bearing complexed or un-complexed pyridine rings

- Paolino M. - Saletti M. - Reale A. - Razzano V. - Giuliani G. - Alessandro Donati - Claudia Bonechi - Giorgi G. - Andrea Atrei - Mauro M. - Scamporrino A. - Samperi F. - Fois E. - Tabacchi G. - Botta C. - Cappelli A.
European Polymer Journal

Lipids from algal biomass provide new (nonlamellar) nanovectors with high carrier potentiality for natural antioxidants

- Clemente I. - Claudia Bonechi - Rodolfi L. - Bacia-Verloop M. - Claudio Rossi - Sandra Ristori
European Journal of Pharmaceutics and Biopharmaceutics

see all publications...